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                                                                        CHILDHOOD CANCER MENU
                                                                            • What is cancer?
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                                                                        Acute Lymphblastic Leukaemia
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                                                                         • Facts and Statistics

                                                                        The above pages are intended to back up the information you get from the hospital, not to replace medical advice from a consultant.

                                                                        Facts and Statistics

                                                                                • The term ‘childhood cancer’ is defined as tumours affecting those in the population under the age of 15 years.
                                                                                • Childhood cancers are generally very different to those seen in adults.
                                                                                • Childhood cancers can be grouped into twelve types:
                                                                                • Cancer is relatively rare in children, accounting for 0.5% of all cancers.
                                                                                • In the UK around 1,500* children are diagnosed with cancer each year.
                                                                                • Around 1 in 500 children in Britain will develop some form of cancer by 14 years of age.
                                                                                • Leukaemia is the most commonly diagnosed cancer in children.
                                                                                • Leukaemia and brain tumours account for more than half of all cancers in childhood.
                                                                                • In Britain childhood cancer incidence rates have increased by over 40% since the late 1960s.
                                                                                • Throughout Europe, childhood cancer incidence rates are lowest in the British Isles and highest in Northern Europe.
                                                                        How many children survive cancer?
                                                                                • More children than ever are surviving cancer.
                                                                                • The survival rate for children’s cancer has more than doubled since the 1960s.
                                                                                • It is estimated that there are around 26,000 childhood cancer survivors in Britain.
                                                                                • Almost three-quarters of children with cancer are now cured of their disease, compared with around a quarter in the late 1960s
                                                                                • For every ten children diagnosed with cancer, almost eight now survive for five years or more, compared with fewer than three in ten in the late 1960s
                                                                                • Eight out of ten children with leukaemia now survive for five years or more. In the late 1960s only one in ten survived.
                                                                                • Nearly all children diagnosed with retinoblastoma (a type of eye cancer) are cured.
                                                                                • Five year survival rates for children with hepatoblastoma (a type of liver cancer) have more than trebled since the late 1970s.
                                                                                • Survival rates for children with rhabdomyosarcoma (a type of muscle cancer) have doubled since the early 1970s.
                                                                                • Now eight out of ten children survive kidney cancer compared to only six in ten in the early 1970s.
                                                                                • Around six out of ten children with neuroblastoma (a cancer of the nerve tissue) are cured.
                                                                        How many children die from cancer?
                                                                                • In the UK cancer is the leading cause of death from disease in children aged 1-14 years and accounts for just under a fifth of all deaths in this age group.
                                                                                • Almost 300* children die from cancer each year in the UK.
                                                                                • Brain and central nervous system (CNS) tumours are the most common cause of childhood cancer death.
                                                                                • Thanks to many years of dedicated research, the death rate for children with cancer has more than halved since the 1960s.
                                                                        What are the main causes of childhood cancer?
                                                                                • Very little is known about the causes of most childhood cancers.
                                                                                • Several rare genetic syndromes, such as Fanconi anaemia and Li-Fraumeni syndrome, are associated with an increased risk of certain childhood cancers.
                                                                                • There is evidence that some childhood leukaemias may develop after an abnormal response to infection early in life.
                                                                                • Children with Down’s syndrome are at a greater risk of developing leukaemia.
                                                                                • Two in five retinoblastomas (a type of eye cancer) are caused by an inherited faulty gene.
                                                                                • Most studies have shown no evidence for an increase in risk of electromagnetic sources such as power lines and domestic wiring
                                                                                • The high incidence of certain childhood cancers in some regions of the world is linked with infections by viruses such as Epstein-Barr, hepatitis B and human herpes virus 8.
                                                                                • Some children treated with radiotherapy and/or chemotherapy are at a greater risk of developing a second primary cancer.

                                                                        * Average of the last three years
                                                                        Source: facts and figures from
                                                                        www.cancerresearchuk.org
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